MyBioSource.com's HDAC10 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Western Blot. The HDAC10 Antibody was generated using HD10 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Jenny J. Tong, Nucleic Acids Res., Mar 2002; 30: 1114 - 1123.Hung-Ying Kao, J. Biol. Chem., Jan 2002; 277: 187 - 193.Denise D. Fischer, J. Biol. Chem., Feb 2002; 277: 6656 - 6666.Matthew H. Brush, J. Biol. Chem., Feb 2004; 279: 7685 - 7691